产品货号：
Z38003
中文名称：
Gamma Catenin/JUP抗体
英文名称：
Anti-Gamma Catenin/JUP Antibody (Clone#4C12D7)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Gamma Catenin/JUP Antibody (Clone#4C12D7) |
| 指标别名 | γ-Catenin;ARVD12;Catenin gamma;CTNNG;Desmoplakin 3;Desmoplakin III;DP3;DPIII;junction plakoglobin;JUP;gamma Catenin;PDGB;PKGB |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | JUP |
| 克隆号 | 4C12D7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | E.coli-derived human gamma Catenin recombinant protein (Position:M556-A745).Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin. |
| 实际分子量 | 82KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Junction plakoglobin(JUP),also known as gamma-catenin,is a protein that in humans is encoded by the JUP gene.It is a member of the catenin protein family and homologous to β-catenin,and it is mapped to 17q21.2.This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions.This protein forms distinct complexes with cadherins and desmosomal cadherins.Meanwhile,JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes. |
| Uniprot ID | P14923 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | junction plakoglobin |
| 蛋白名全称 | Junction plakoglobin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow Cytometry (FCM) 1～3μg/1×106 cells Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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